What Are the Effects of Rejuran Injection? Explaining Why Some Say It Is Ineffective

Rejuran Injection is a treatment in which Rejuran, a product rich in the salmon-derived beauty ingredient “polynucleotide,” is injected directly into the skin. It is also referred to as high-concentration salmon injection.

Rejuran Injection may be highly effective for signs of skin aging that appear with age, such as wrinkles, spots, sagging, and enlarged pores. It can be used not only on the face but also on areas such as the neck and backs of the hands.

The main beauty ingredient in Rejuran, “polynucleotide,” is extracted from salmon DNA. Polynucleotides have the following effects:

Through these effects, Rejuran Injection may provide cosmetic benefits by transforming weakened skin into youthful-looking, firm skin.

Here are some of the main effects that may be achieved through Rejuran Injection treatment.

Polynucleotides, one of Rejuran’s beauty ingredients, work to activate cells.

Polynucleotides help regenerate, form, and activate capillaries. This allows nutrients to be delivered through the blood to every part of the body, helping boost metabolism. In skin with an enhanced metabolism, cell turnover is promoted, replacing old skin cells with new ones. In this way, the skin is regenerated into youthful-looking skin with moisture and clarity.

This effect may be difficult to notice immediately after Rejuran Injection is administered. Skin regeneration naturally requires time. Therefore, it may take several weeks to several months before the effects are felt.

The dermal layer of the skin contains large amounts of collagen, elastin, and hyaluronic acid, which are essential for skin firmness, elasticity, and moisture. However, as we age, production of these substances decreases, causing skin aging to progress.

Rejuran helps activate fibroblasts in the dermal layer, promoting the production of collagen, elastin, and hyaluronic acid. When these substances are produced, the skin gains firmness, elasticity, and moisture, which may help improve wrinkles, sagging, and nasolabial folds.

Rejuran may help improve skin problems caused by inflammation and other factors. This can make rough skin and acne less likely to occur. In addition, skin regeneration through cell turnover helps smooth uneven skin caused by rough skin and acne scars, leading to smoother-looking skin.

The effects of cell turnover also work on the tissue around the pores. Rejuran can help regulate sebum production and tighten the pores. As the pores become tighter, skin problems such as acne may become even less likely to occur.

Under-eye dark circles can suggest a lack of sleep or fatigue, often creating a dark impression that makes a person appear older than their actual age. Rejuran can be highly effective for these under-eye dark circles.

There are several causes of under-eye dark circles. One is that blood becomes dark due to poor circulation and shows through the thin skin under the eyes. Another is that the weakening of the skin and muscles under the eyes creates hollows, which can appear dark because of the resulting shadows.

Rejuran can also be injected around the eyes. Injecting it under the eyes promotes blood flow and generates collagen in the dermal layer, creating firmness. As a result, the eye area becomes brighter, hollows improve, and the area takes on a fuller appearance.

The effects of Rejuran Injection appear gradually. Generally, the effects begin to be noticeable after about 2–3 weeks. This is the time required for the skin to change as a result of Rejuran’s effects.

The effects of Rejuran last for several months to around six months. Although results vary from person to person, once Rejuran has acted on the skin’s functions, its effects continue until those functions weaken due to aging, lifestyle habits, or other factors.

Rejuran Injection offers significant cosmetic benefits and has an established track record. However, some people say that it is “ineffective.” We will explain why this may be said, taking the characteristics of Rejuran Injection into account.

Rejuran Injection works on fibroblasts in the dermal layer and promotes cell turnover, gradually transforming the skin into new skin. It takes several weeks to several months for the skin to slowly regenerate.

If you expected a clear change immediately after treatment, as with Hyaluronic Acid Injection, the gradual changes from Rejuran Injection may be difficult to notice, and you may feel that it is “ineffective.”

Rejuran Injection is a treatment whose effects appear when there are certain problems with the skin. These include skin problems such as age-related wrinkles and sagging, rough skin, and acne, and Rejuran Injection may be effective for such concerns.

On the other hand, changes from Rejuran Injection may be limited in young, healthy, and beautiful skin with few problems, making the effects more difficult to notice.

However, even in young and beautiful skin, Rejuran Injection can improve skin problems that have not yet appeared on the surface from within, helping prevent skin problems that may arise later.

Rejuran Injection offers significant effects, but what benefits can be expected from undergoing the treatment?

Rejuran Injection can be injected into various areas of concern on the skin, such as wrinkles. Specific areas include the following.

Rejuran Injection promotes cell turnover and can improve various skin problems. Because it works directly on the cells, its effects appear gradually from within the skin. As a result, the injection sites do not change unnaturally, and the skin becomes balanced with a natural, beautiful appearance.

The effects of Rejuran last for several months to around six months. Because Rejuran conditions the skin at the cellular level, the improved condition continues until the skin deteriorates again, helping maintain the improved condition for a long time.

The effects of Rejuran can be enhanced when it is combined with other treatments.

One possible combination is Derma Pen. Derma Pen uses ultra-fine needles to create numerous tiny holes in the dermal layer, promoting the skin’s wound-healing ability to improve the skin. Combining Derma Pen with Rejuran may produce a synergistic effect by activating cells from within as well.

The main beauty ingredient in Rejuran, “polynucleotide,” is extracted from salmon DNA and has a structure similar to human DNS. Therefore, it is said to blend easily with the human body and have a high level of safety, with very few side effects such as allergic reactions.

Let us look at the disadvantages and precautions associated with Rejuran Injection.

Because a needle is inserted during Rejuran Injection, the procedure will inevitably cause pain if performed without any measures to reduce it.

For this reason, topical anesthetic or similar measures are generally used during the procedure. Anesthetic can minimize pain during treatment.

Some types of Rejuran products also contain an anesthetic, which can help reduce pain.

The area where the Rejuran product is injected becomes bumpy and swollen, resembling insect bites. The swelling usually settles within several hours to around one day, but the skin is prone to internal bleeding during this period. Therefore, avoid drinking alcohol, strenuous exercise, prolonged bathing, and rubbing the injection sites, as these actions may cause internal bleeding.

Rejuran Injection can produce effects after a single treatment. However, to achieve more substantial effects, receiving treatment regularly about 3–4 times at intervals of 2–3 weeks can help you experience the effects more consistently and maintain them.

Rejuran Injection is a treatment that gradually improves from within skin concerns such as wrinkles, spots, and sagging caused by skin aging, as well as rough skin, acne scars, and pores.

Some people say that it is “ineffective,” but this is because changes resulting from cell activation require time. In addition, the effects of Rejuran Injection become visible when there are certain problems with the skin, so the effects may be difficult to notice in people with beautiful skin. Nevertheless, Rejuran Injection helps condition and improve the skin from within.

At LIVELY CLINIC, in addition to Rejuran Injection, we also offer an injection treatment called Rapunzel Injection, an original blend of “high-concentration salmon extract,” “micro Botox,” and other skin-beautifying ingredients.

Rapunzel Injection combines the effects of Rejuran with the rapid pore-reducing and sebum-suppressing effects of micro Botox in a single treatment. In addition, because the active ingredients are uniquely blended by our clinic, it is characterized by less pain compared with Rejuran.

It is also more reasonably priced than Rejuran and has been well received by many people.

It is recommended for people who want to improve the appearance of their skin, improve their skin quality, or are concerned about pores and sebum-related problems.

If you are interested in Rejuran Injection or Rapunzel Injection, or if you are concerned about recent changes in your skin and would like to discuss them, please feel free to contact us about anything, no matter how minor.