診療科目

Juvgen

JUVGEN is a groundbreaking treatment that delivers remarkable results for skin concerns previously considered difficult to improve with conventional methods, such as nasolabial folds and acne scars.
Developed in South Korea, this innovative procedure promotes fundamental regeneration from the dermis, achieving natural and long-lasting skin improvement.

What is JUVGEN?

JUVGEN Autologous Dermal Regeneration Therapy is a patented Korean aesthetic medical technique. Using ultra-fine needles, medical-grade carbon dioxide gas and hyaluronic acid are repeatedly injected into the dermis of depressed areas. This stimulates the production of abundant collagen fiber tissue, creating new skin and raising the depressions.

Medical-Grade Carbon Dioxide Gas

Main Effects:
・Promotes blood circulation and boosts metabolism
・Activates autologous fibroblasts
→ Supports collagen reconstruction

High-Molecular Hyaluronic Acid

Main Effects:
・Maintains volume and space
・Provides a scaffold for extracellular matrix formation
→ Builds the foundation for skin regeneration

A fundamentally different approach

Because the procedure is performed beneath the skin surface, it offers exceptional safety. The newly generated collagen tissue in the dermis is permanently maintained, eliminating the need for regular maintenance. Unlike laser treatments, which require repeated sessions, most patients achieve satisfying results in just 1–3 treatments.

Three Key Points to Consider When Using Juvgen

1. Semi-permanent Results with Your Own Collagen
Juvgen is not a treatment that leaves injected ingredients in place, but rather stimulates the skin's own collagen production.
As a result, rather than a temporary effect, it creates a process of skin transformation.

2. Natural-looking Results Without Injections
Rather than injecting a foreign substance like hyaluronic acid to create shape, Juvgen utilizes the skin's natural regenerative powers, resulting in a natural-looking finish without the appearance of unnatural volume.

3. International Patents Ensure High Safety
Juvgen has 20 patents registered or pending in countries including the United States, South Korea, Japan, and China, and safety is a key consideration in the formulation and treatment design. (As of 2025) *Treatment is performed under the supervision of a physician.

What you can expect from Juvgen

Improving Nasolabial Folds

Juvgen is a treatment that can potentially improve nasolabial folds, which deepen with age. Unlike traditional hyaluronic acid injections, it provides a more natural and long-lasting improvement.
While hyaluronic acid is absorbed by the body over time, the collagen tissue produced by Juvgen is maintained permanently, allowing you to maintain a youthful appearance for the long term.
In addition, Juvgen addresses the sagging skin and muscle weakness that cause nasolabial folds by increasing skin volume from within, achieving a natural rejuvenation of the mouth area. The treatment maintains a natural facial expression whether you're expressionless or smiling, allowing you to achieve unnoticed beauty.
Forehead Wrinkles

Juvgen is effective in improving deep wrinkles on the forehead that develop due to aging and contraction of facial muscles. While traditional Botox injections reduce the appearance of wrinkles by stopping the movement of facial muscles, Juvgen stimulates collagen production directly in the dermis, thereby improving the underlying cause of wrinkles.
Visible wrinkles on the face

Juvgen is also effective for noticeable wrinkles across the face, such as marionette lines extending downward from the corners of the mouth and deep wrinkles at the corners of the eyes. These wrinkles are formed by structural changes occurring deep within the skin, so superficial treatment alone has its limits.
Acne scars and craters

Juvgen is also effective on crater-like depressions caused by acne scars. It is particularly effective on ice pick-shaped and boxcar-shaped acne scars that reach deep into the dermis layer.
Even for severe craters that would require 10 or more treatments with conventional laser treatments, Juvgen can sometimes show clear improvement with just one or two treatments.
Scar repair

Juvgen is highly effective in repairing scars (scar tissue) caused by surgery or trauma. By promoting regeneration from the dermis layer, even scars that have traditionally been considered difficult to treat can be expected to become less noticeable. Even old scars can be expected to show significant improvement.

Characteristics of JUVGEN at our clinic

Introduced in Japan from the very beginning

Our clinic was one of the first to introduce Juvgen (autologous dermal regeneration) in Japan, and boasts an extensive track record and extensive caseload in the field of skin regeneration.
Our extensive experience addressing the concerns of many patients allows us to flexibly address a wide range of concerns.
Developer-Certified Clinic

Lively Clinic is officially certified by Juvgen's developer, Juvgen's Chen Plastic Surgery Clinic.
Our head physician also received direct training under Director Jin Se-hoon at Juvgen's developer, Juvgen's Chen Plastic Surgery Clinic in Seoul, Korea. We incorporate the cutting-edge techniques learned locally and provide our services to patients in Japan with a focus on safety.
Officially Certified Clinic with International KOL Doctors

Lively Clinic has an official partnership with Juvgen's development center, Jin Plastic Surgery Clinic in Seoul, Korea.
The developer has established a certification system that allows only doctors with the appropriate skills and knowledge to perform the procedure, strictly controlling the quality of practitioners.
Certified physicians receive specialized training in anatomical knowledge, injection techniques, and how to deal with complications.
In addition, treatment protocols are standardized, ensuring consistent treatment quality that is not dependent on the skill of individual physicians.

When receiving Juvgen in Japan, choose Lively Clinic.
Officially Certified Juvgen Educational Facility

Our clinic, led by our lead physician, is dedicated to educational activities aimed at passing on Juvgen's correct theories and techniques nationwide.

Based on the latest domestic and international knowledge, we hold regular study sessions and practical training sessions for physicians and medical professionals, striving to promote safe and effective treatments.

*A KOL (Key Opinion Leader) is someone with specialized knowledge and achievements in a specific field whose statements and information influence the decisions of many people.

Juvgen case studies

Case study before Juvgen treatment
Case study of Juvgen treatment 1 month later
Case study 6 months after Juvgen treatment

Treatment Flow

1Reservation
2Visit to the clinic
3Examination & Consultation
4Contract/Agreement
5Application of numbing cream (about 30 minutes before the procedure)
6Procedure (procedure time varies depending on the treatment area, but generally completed within 15–20 minutes)
7Post-procedure care

※Please keep the treated area as clean as possible for three days after the treatment. Also, please be careful not to touch the treated area with your hands unnecessarily.

Possible side effects / risks	Temporary swelling and bruising may occur, typically resolving within a few days to two weeks. Rarely, allergic reactions or pustular acne may develop.
Pain	Some pain may occur during injection, and mild soreness may persist for several days. If you are sensitive to pain, consult your physician.
face washing/bathing	Do not wash your face for 12 hours after treatment. Afterwards, use a gentle foaming face wash to avoid friction.
Makeup	Please avoid wearing makeup for two days after the procedure. Even after that, please avoid applying heavy foundation.
Alcohol/Work out	Avoid alcohol, sauna, and intense exercise for several days after treatment.
After care	Avoid touching the treated area for about one week. If needed, hyaluronidase can be used for correction within 2 weeks post-treatment.
Contraindications	Not suitable for individuals with bleeding disorders, those who are pregnant or may be pregnant, those with a history of allergic reactions to hyaluronic acid or anesthesia, those with local infections, keloid tendencies, or skin diseases.

FAQ FAQ

Is anesthesia available?: We provide numbing cream. It will be applied about 30 minutes before the procedure begins, so even those who feel anxious can undergo the treatment with peace of mind.

What kind of results can I expect from Juvzen treatment?: Juvzen is a treatment that can be expected to be effective in improving wrinkles, scars, and acne scars. Many people notice a change in about a week after just one treatment, and the results will become more natural over the course of 3 to 6 months. Another major feature is that the effects last for a long time.

How long do the effects last?: The collagen tissue generated by the treatment becomes part of your own skin tissue and is essentially permanent.
However, natural aging cannot be avoided, so some patients choose additional treatments after several years for maintenance.

What does it feel like during a Juvzen treatment?: You may feel a slight stinging pain from the needle when you inject.

How long does a Juvzen treatment take?: Treatment time varies depending on the area being treated, but generally takes 15 to 20 minutes to complete.

Will it cause lumps?: Since Juvezen stimulates collagen production, the tissue may temporarily feel firm during the regeneration process.
This is a natural response, similar to how an injury area may feel firm while healing.
For several months after the procedure, you may feel a firmness resembling a lump, but it will naturally improve over time.

Are there any risks, downtime or side effects?: After the treatment, redness and swelling may occur at the injection site. This is a normal reaction and usually improves within a few days to two weeks. In rare cases, allergic reactions or purulent acne may occur.

How many sessions and at what intervals are recommended?: For younger patients or those with mild symptoms, a single treatment may be sufficient for noticeable improvement.
For more severe cases, we may recommend around three sessions.
The usual interval is once every 2–3 months, but the exact plan will be proposed after examining your skin and symptoms during the consultation.

Juvgen